Endocrine Abstracts

Introduction: Primary hyperparathyroidism is frequent; it can be ectopic in 11 to 25% of cases, the mediastinal position is the most frequent ectopic position, but the intrapericardial position is exceptional.Clinical Case: A 58 year old woman with primary hyperparathyroidism complicated by severe osteoporosis. The CT scan and parathyroid scintigraphy reveals a 17 mm parathyroid adenoma in the mediastinal aortopulmonary position. After a first thoracic s...

Introduction: Tuberculosis is a granulomatosis with systemic manifestations. Pulmonary involvement is usually in the foreground. Rarely, hypercalcaemia initiates the pathology. The incidence of hypercalcaemia in tuberculosis varies according to studies and regions between 2 and 25%, with the highest incidences in the most isolated countries and those with the highest calcium and vitamin D intakes.Clinical Case: This is the case of our patient known for b...

Although rare in children, Graves’ disease remains the major cause of hyperthyroidism. Positive diagnosis is easy, but management can be extremely problematic.Case Report: We report the case of a 13 year old female patient treated for Graves’ disease since 4 years; non compliant to treatment; after adjustment of therapy and achievement of euthyroidism; a surgical cure is programmed. 24 hours after surgery, severe hypocalcaemia appeared, requiri...

Introduction: The treatment of prolactin adenomas is medical based on the use of dopaminergic agonists but the presence of an underlying valvulopathy makes the treatment by cabergoline delicate.Clinical case: We report the case of a 60 year old female patient, operated on for aortic valve disease, with moderate mitral leakage. On the occasion of a decrease in visual acuity; a prolactin macro adenoma is diagnosed In agreement with the cardiologist; we opt...

Introduction: The most frequent cystic lesions in the pituitary region are: cystic adenomas, Rathke’s pouch cysts and craniopharyngiomas. But sometimes the diagnosis can be difficult.Clinical case: This is the case of a women patient who consulted at the age of 20 for a pituitary cystic process revealed by secondary amenorrhoea; evoking in the first place a Rathke’s pouch cyst. Hormonal assessment reveals tumour-related hyperprolactinemia; the ...

Introduction: Maccune albright syndrome; is a rare disorder resulting from the involvement of several organs; the phenotype is variable depending on the clinical manifestations linked to the importance of the tissues affected by the mutation.Case report: In our patient, the diagnosis was not made until she was 8 years old, despite some suggestive signs: as café au lait skin macules at birth and early forearm bone fractures at the age of 3 years. At ...

Introduction: Pituitary hyperplasia, defined as an increase in the size of the pituitary gland, is rare in children; the main etiology is the onset of puberty. We report the case of a 15-year-old girl with Growth retardation and amenorrhea. The exploration of the pituitary region revealed pituitary hyperplasia measuring 18 mm x 13 mm. Karyotype revealed Turner mosaic syndrome. Discussion: In our patient, the hyperplasia was secondary to thyroid cell prol...

Introduction: Prolactinoma is the most common pituitary tumour; in the majority of cases it is a microadenoma.Materials and methods: Through a retrospective study of 46 patients followed for macro prolactin adenomas we evaluate the response to medical treatment of macroprolactinoma. In our series, macroprolactinomas are more frequent in men (59%), more often diagnosed between the ages of 25 and 45. As expected, cranial tumour syndrome remains the main re...

Introduction: Warthin-like thyroid tumor (WLPTC) is a rare variant of papillary thyroid carcinoma characterized by a lymphoid stroma. Approximately 95 observations have been published in the literature. Like papillary carcinoma, Warthin-like thyroid tumors have a good prognosis. The key to diagnosis is anatomopathological examination. In this regard, we report a case of WLPTC because of its rarity.Observation: Patient aged 56, known diabetic for 6 years ...

Introduction: Graves’ disease is a rare and severe condition, affecting mainly younger children. Its appropriate management in children remains a subject of controversy in pediatric endocrinology, and the optimal duration of medical treatment to induce remission of the disease, as well as the indications for alternative therapies, remain to be defined.Observation: This is a 15-year-old child who presented at the age of 13 years and 10 months with ty...